Varaico: Literature-Extracted Genetic Variants

GRAP2

978 papers

RefSeq Summary

This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-re...

Pfam Domains

SH3_1aa 4–48UCSCSH3 domain

SH2aa 58–132UCSCSH2 domain

SH3_1aa 277–322UCSCSH3 domain

Gene Aliases

HGNC Name

GRB2 related adaptor protein 2

HGNC Alias Symbols

Grf40; GrbX; GRBLG; GADS; Mona

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004810.4

p.Y45N

c.133T>A

Surrounding Variants

1 paper

NM_004810.4

p.Y45_V46delFs

c.135_136delTG

1 paper

NM_004810.4

p.E43A

c.128A>C

2 papers

NM_004810.4

p.P47S

c.139C>T

1 paper

NM_004810.4

p.E43K

c.127G>A

1 paper

NM_004810.4

p.P47R

c.140C>G

1 paper

NM_004810.4

p.Q42_G44del0

c.125_130del6

1 paper

NM_004810.4

p.K48R

c.143A>G

1 paper

NM_004810.4

p.S41G

c.121A>G

1 paper

NM_004810.4

p.N49I

c.146A>T

1 paper

NM_004810.4

p.G40R

c.118G>A

1 paper

NM_004810.4

p.F50L

c.148T>C

1 paper

NM_004810.4

p.F50L

c.150C>A