Varaico: Literature-Extracted Genetic Variants

Gene:GRB2
Variant:p.F9L

GRB2

185 papers

RefSeq Summary

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of o...

Pfam Domains

SH3_1aa 4–50UCSCSH3 domain
SH2aa 60–135UCSCSH2 domain
SH3_1aa 162–207UCSCSH3 domain

Gene Aliases

HGNC Name

growth factor receptor bound protein 2

HGNC Alias Symbol

NCKAP2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002086.5
p.F9L
c.27C>A
Surrounding Variants
2 papers
NM_002086.5
p.F9L
c.27C>G
2 papers
NM_002086.5
p.F9L
c.25T>C
3 papers
NM_002086.5
p.Y7F
c.20A>T
1 paper
NM_002086.5
p.Y7D
c.19T>G
1 paper
NM_002086.5
p.A13A
c.39A>G
2 papers
NM_002086.5
p.A5P
c.13G>C
1 paper
NM_002086.5
p.L17R
c.50T>G
1 paper
NM_002086.5
p.E2Q
c.4G>C
1 paper
NM_002086.5
p.D23_I24del1
c.68_70delTGT
1 paper
NM_002086.5
p.K20_K26insFs
c.59_77dup19
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