Varaico: Literature-Extracted Genetic Variants

GRIA4

166 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeri...

Pfam Domains

ANF_receptoraa 39–382UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 415–530UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 544–825UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor AMPA type subunit 4

HGNC Previous Symbol

GLUR4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000829.4

p.R697Q

c.2090G>A

Surrounding Variants

2 papers

NM_000829.4

p.R697P

c.2090G>C

1 paper

NM_000829.4

p.E710A

c.2129A>C

1 paper

NM_000829.4

p.E710D

c.2130G>C

1 paper

NM_000829.4

p.E710D

c.2130G>T

3 papers

NM_000829.4

p.E727Q

c.2179G>C

3 papers

NM_000829.4

p.E727A

c.2180A>C

4 papers

NM_000829.4

p.E727D

c.2181G>C

4 papers

NM_000829.4

p.E727D

c.2181G>T

1 paper

NM_000829.4

p.T729A

c.2185A>G

1 paper

NM_000829.4

p.R737*

c.2209C>T

1 paper

NM_000829.4

p.A757T

c.2269G>A

1 paper

NM_000829.4

p.G761V

c.2282G>T