Varaico: Literature-Extracted Genetic Variants

GRIK2

299 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 52–397UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 431–546UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 560–831UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 2

HGNC Previous Symbol

GLUR6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_021956.5

p.I567V

c.1699A>G

Surrounding Variants

1 paper

NM_021956.5

p.Y566C

c.1697A>G

1 paper

NM_021956.5

p.W564L

c.1691G>T

8 papers

NM_021956.5

p.Y571C

c.1712A>G

1 paper

NM_021956.5

p.G573S

c.1717G>A

1 paper

NM_021956.5

p.A582T

c.1744G>A

1 paper

NM_021956.5

p.I540V

c.1618A>G

1 paper

NM_021956.5

p.T535S

c.1603A>T

1 paper

NM_021956.5

p.M534L

c.1600A>C

1 paper

NM_021956.5

p.M534L

c.1600A>T

1 paper

NM_021956.5

p.P532P

c.1596C>T

1 paper

NM_021956.5

p.K531E

c.1591A>G

1 paper

NM_021956.5

p.D528A

c.1583A>C