Varaico: Literature-Extracted Genetic Variants

GRIK2

299 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 52–397UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 431–546UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 560–831UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 2

HGNC Previous Symbol

GLUR6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021956.5

p.F614Y

c.1841T>A

Surrounding Variants

1 paper

NM_021956.5

p.G615A

c.1844G>C

1 paper

NM_021956.5

p.G615G

c.1845A>G

1 paper

NM_021956.5

p.M620V

c.1858A>G

1 paper

NM_021956.5

p.M620R

c.1859T>G

9 papers

NM_021956.5

p.Q621R

c.1862A>G

1 paper

NM_021956.5

p.Q622R

c.1865A>G

1 paper

NM_021956.5

p.D600G

c.1799A>G

1 paper

NM_021956.5

p.P597R

c.1790C>G

1 paper

NM_021956.5

p.P597A

c.1789C>G

1 paper

NM_021956.5

p.N596H

c.1786A>C

1 paper

NM_021956.5

p.C595S

c.1784G>C

1 paper

NM_021956.5

p.C595S

c.1783T>A