Varaico: Literature-Extracted Genetic Variants

GRIK2

299 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 52–397UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 431–546UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 560–831UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 2

HGNC Previous Symbol

GLUR6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021956.5

p.W641C

c.1923G>C

Surrounding Variants

1 paper

NM_021956.5

p.W641C

c.1923G>T

1 paper

NM_021956.5

p.I635L

c.1903A>T

1 paper

NM_021956.5

p.S650L

c.1949C>T

1 paper

NM_021956.5

p.A653S

c.1957G>T

8 papers

NM_021956.5

p.A657T

c.1969G>A

4 papers

NM_021956.5

p.T660K

c.1979C>A

2 papers

NM_021956.5

p.T660R

c.1979C>G

1 paper

NM_021956.5

p.E662D

c.1986A>C

1 paper

NM_021956.5

p.E662D

c.1986A>T

1 paper

NM_021956.5

p.R663S

c.1987C>A

1 paper

NM_021956.5

p.R663C

c.1987C>T

1 paper

NM_021956.5

p.S666A

c.1996T>G