Varaico: Literature-Extracted Genetic Variants

GRIK2

299 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 52–397UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 431–546UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 560–831UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 2

HGNC Previous Symbol

GLUR6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_021956.5

p.V685L

c.2053G>T

Surrounding Variants

1 paper

NM_021956.5

p.V685I

c.2053G>A

2 papers

NM_021956.5

p.V685L

c.2053G>C

1 paper

NM_021956.5

p.V685E

c.2054T>A

1 paper

NM_021956.5

p.D687A

c.2060A>C

1 paper

NM_021956.5

p.D687G

c.2060A>G

1 paper

NM_021956.5

p.A689T

c.2065G>A

1 paper

NM_021956.5

p.A689S

c.2065G>T

1 paper

NM_021956.5

p.A689G

c.2066C>G

1 paper

NM_021956.5

p.A689V

c.2066C>T

1 paper

NM_021956.5

p.T690A

c.2068A>G

1 paper

NM_021956.5

p.M691K

c.2072T>A

1 paper

NM_021956.5

p.M691I

c.2073G>A