Varaico: Literature-Extracted Genetic Variants

GRIK2

299 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 52–397UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 431–546UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 560–831UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 2

HGNC Previous Symbol

GLUR6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_021956.5

p.S868A

c.2602T>G

Surrounding Variants

14 papers

NM_021956.5

p.M867I

c.2601G>A

14 papers

NM_021956.5

p.M867I

c.2601G>C

14 papers

NM_021956.5

p.M867I

c.2601G>T

1 paper

NM_021956.5

p.E864E

c.2592A>G

1 paper

NM_021956.5

p.R873C

c.2617C>T

2 papers

NM_021956.5

p.R873H

c.2618G>A

3 papers

NM_021956.5

p.R874Q

c.2621G>A

1 paper

NM_021956.5

p.L875fs

c.2623_2624fs

1 paper

NM_021956.5

p.L875*

c.2624T>A

1 paper

NM_021956.5

p.L875*

c.2624T>G

1 paper

NM_021956.5

p.L875_V885delFs

c.2625_2655del31

1 paper

NM_021956.5

p.P879A

c.2635C>G