Varaico: Literature-Extracted Genetic Variants

GRIK3

180 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 55–400UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 434–548UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 562–832UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 3

HGNC Alias Symbols

GluK3; GLUR7

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000831.4

p.I637T

c.1910T>C

Surrounding Variants

3 papers

NM_000831.4

p.R636C

c.1906C>T

1 paper

NM_000831.4

p.S652F

c.1955C>T

2 papers

NM_000831.4

p.R665H

c.1994G>A

1 paper

NM_000831.4

p.K678R

c.2033A>G

1 paper

NM_000831.4

p.G625Splc

c.1874-126G>A

1 paper

NM_000831.4

p.Q623K

c.1867C>A

1 paper

NM_000831.4

p.V604A

c.1811T>C

1 paper

NM_000831.4

p.F586V

c.1756T>G

1 paper

NM_000831.4

p.V582I

c.1744G>A

1 paper

NM_000831.4

p.S577I

c.1730G>T

1 paper

NM_000831.4

p.A572T

c.1714G>A

1 paper

NM_000831.4

p.L561M

c.1681C>A