Varaico: Literature-Extracted Genetic Variants

GRIK3

180 papers

RefSeq Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to t...

Pfam Domains

ANF_receptoraa 55–400UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 434–548UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 562–832UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 3

HGNC Alias Symbols

GluK3; GLUR7

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000831.4

p.R136C

c.406C>T

Surrounding Variants

1 paper

NM_000831.4

p.V150M

c.448G>A

1 paper

NM_000831.4

p.V121I

c.361G>A

1 paper

NM_000831.4

p.N119N

c.357T>C

1 paper

NM_000831.4

p.P154H

c.461C>A

1 paper

NM_000831.4

p.D155N

c.463G>A

1 paper

NM_000831.4

p.A157T

c.469G>A

1 paper

NM_000831.4

p.L159P

c.476T>C

1 paper

NM_000831.4

p.R173Q

c.518G>A

1 paper

NM_000831.4

p.Q189R

c.566A>G

1 paper

NM_000831.4

p.R205C

c.613C>T

2 papers

NM_000831.4

p.R215H

c.644G>A

1 paper

NM_000831.4

p.R223*

c.667C>T