Varaico: Literature-Extracted Genetic Variants

Gene:GRIK4
Variant:p.A28Splc

GRIK4

134 papers

RefSeq Summary

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of l...

Pfam Domains

ANF_receptoraa 40–384UCSCReceptor family ligand binding region
Lig_chan-Glu_bdaa 416–530UCSCLigated ion channel L-glutamate- and glycine-binding site
Lig_chanaa 544–816UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 4

HGNC Alias Symbols

GluK4; KA1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_014619.5
p.A28Splc
c.83-10039T>C
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