Varaico: Literature-Extracted Genetic Variants

GRIK4

134 papers

RefSeq Summary

This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of l...

Pfam Domains

ANF_receptoraa 40–384UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 416–530UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 544–816UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor kainate type subunit 4

HGNC Alias Symbols

GluK4; KA1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014619.5

p.M824T

c.2471T>C

Surrounding Variants

1 paper

NM_014619.5

p.L825W

c.2474T>G

1 paper

NM_014619.5

p.F827V

c.2479T>G

1 paper

NM_014619.5

p.H833insFs

c.2497dupC

1 paper

NM_014619.5

p.M802I

c.2406G>A

1 paper

NM_014619.5

p.M802I

c.2406G>C

1 paper

NM_014619.5

p.M802I

c.2406G>T

1 paper

NM_014619.5

p.G801A

c.2402G>C

1 paper

NM_014619.5

p.G799G

c.2397C>A

1 paper

NM_014619.5

p.H860P

c.2579A>C

1 paper

NM_014619.5

p.R872L

c.2615G>T

1 paper

NM_014619.5

p.A895T

c.2683G>A

1 paper

NM_014619.5

p.L905_A909delins

c.2713_2727delinsGCT