Varaico: Literature-Extracted Genetic Variants

GRIN2D

179 papers

RefSeq Summary

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficie...

Pfam Domains

ANF_receptoraa 80–317UCSCReceptor family ligand binding region

Lig_chan-Glu_bdaa 474–569UCSCLigated ion channel L-glutamate- and glycine-binding site

Lig_chanaa 582–856UCSCLigand-gated ion channel

Gene Aliases

HGNC Name

glutamate ionotropic receptor NMDA type subunit 2D

HGNC Previous Symbol

NMDAR2D

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_000836.4

p.S694R

c.2082T>G

Surrounding Variants

3 papers

NM_000836.4

p.S694R

c.2082T>A

3 papers

NM_000836.4

p.S694R

c.2080A>C

4 papers

NM_000836.4

p.R696H

c.2087G>A

6 papers

NM_000836.4

p.M681I

c.2043G>A

6 papers

NM_000836.4

p.M681I

c.2043G>C

6 papers

NM_000836.4

p.M681I

c.2043G>T

3 papers

NM_000836.4

p.A678D

c.2033C>A

1 paper

NM_000836.4

p.A675V

c.2024C>T

3 papers

NM_000836.4

p.A675T

c.2023G>A

1 paper

NM_000836.4

p.T674K

c.2021C>A

4 papers

NM_000836.4

p.L670F

c.2008C>T

19 papers

NM_000836.4

p.V667I

c.1999G>A