Varaico: Literature-Extracted Genetic Variants

Gene:GRK1
Variant:p.V282M

GRK1

200 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initia...

Pfam Domains

RGSaa 57–174UCSCRegulator of G protein signaling domain
Pkinaseaa 190–455UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 1

HGNC Previous Symbol

RHOK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002929.3
p.V282M
c.844G>A
Surrounding Variants
1 paper
NM_002929.3
p.E285G
c.854A>G
1 paper
NM_002929.3
p.Y277fs
c.829_830fs
1 paper
NM_002929.3
p.R276Splc
c.828-2A>G
1 paper
NM_002929.3
p.P292L
c.875C>T
1 paper
NM_002929.3
p.P292P
c.876G>A
1 paper
NM_002929.3
p.R293H
c.878G>A
2 papers
NM_002929.3
p.A294T
c.880G>A
1 paper
NM_002929.3
p.T298A
c.892A>G
2 papers
NM_002929.3
p.T298M
c.893C>T
1 paper
NM_002929.3
p.A299V
c.896C>T
1 paper
NM_002929.3
p.E306*
c.916G>T
6 papers
NM_002929.3
p.L308P
c.923T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."