Varaico: Literature-Extracted Genetic Variants

Gene:GRK1
Variant:p.L324delFs

GRK1

200 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initia...

Pfam Domains

RGSaa 57–174UCSCRegulator of G protein signaling domain
Pkinaseaa 190–455UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 1

HGNC Previous Symbol

RHOK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002929.3
p.L324delFs
c.971delT
Surrounding Variants
1 paper
NM_002929.3
p.L324fs
c.970_971fs
1 paper
NM_002929.3
p.L325P
c.974T>C
1 paper
NM_002929.3
p.D328V
c.983A>T
1 paper
NM_002929.3
p.L318H
c.953T>A
1 paper
NM_002929.3
p.R316H
c.947G>A
4 papers
NM_002929.3
p.R316S
c.946C>A
6 papers
NM_002929.3
p.L308P
c.923T>C
1 paper
NM_002929.3
p.E306*
c.916G>T
1 paper
NM_002929.3
p.A299V
c.896C>T
2 papers
NM_002929.3
p.T298M
c.893C>T
1 paper
NM_002929.3
p.T298A
c.892A>G
2 papers
NM_002929.3
p.A294T
c.880G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."