Varaico: Literature-Extracted Genetic Variants

Gene:GRK1
Variant:p.V380D

GRK1

200 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initia...

Pfam Domains

RGSaa 57–174UCSCRegulator of G protein signaling domain
Pkinaseaa 190–455UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 1

HGNC Previous Symbol

RHOK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
15 papers
NM_002929.3
p.V380D
c.1139T>A
Surrounding Variants
1 paper
NM_002929.3
p.V380fs
c.1138_1139fs
2 papers
NM_002929.3
p.V380F
c.1138G>T
1 paper
NM_002929.3
p.G379E
c.1136G>A
1 paper
NM_002929.3
p.V380delFs
c.1138delG
4 papers
NM_002929.3
p.A377P
c.1129G>C
1 paper
NM_002929.3
p.Y383*
c.1149T>A
1 paper
NM_002929.3
p.Y383*
c.1149T>G
1 paper
NM_002929.3
p.E384V
c.1151A>T
1 paper
NM_002929.3
p.A387V
c.1160C>T
1 paper
NM_002929.3
p.Y369Y
c.1107C>T
9 papers
NM_002929.3
p.P391H
c.1172C>A
3 papers
NM_002929.3
p.R393*
c.1177C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."