Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001619.5

p.V7E

c.20T>A

Surrounding Variants

4 papers

NM_001619.5

p.V7A

c.20T>C

1 paper

NM_001619.5

p.V7G

c.20T>G

1 paper

NM_001619.5

p.A6V

c.17C>T

2 papers

NM_001619.5

p.E5A

c.14A>C

1 paper

NM_001619.5

p.A9V

c.26C>T

5 papers

NM_001619.5

p.D10A

c.29A>C

3 papers

NM_001619.5

p.D3A

c.8A>C

1 paper

NM_001619.5

p.D3G

c.8A>G

1 paper

NM_001619.5

p.V11A

c.32T>C

1 paper

NM_001619.5

p.V11G

c.32T>G

1 paper

NM_001619.5

p.D3N

c.7G>A

1 paper

NM_001619.5

p.A2T

c.4G>A