Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001619.5

p.E18A

c.53A>C

Surrounding Variants

1 paper

NM_001619.5

p.E18V

c.53A>T

1 paper

NM_001619.5

p.E18E

c.54G>A

3 papers

NM_001619.5

p.A16V

c.47C>T

1 paper

NM_001619.5

p.Y13F

c.38A>T

2 papers

NM_001619.5

p.A25T

c.73G>A

1 paper

NM_001619.5

p.V11A

c.32T>C

1 paper

NM_001619.5

p.V11G

c.32T>G

5 papers

NM_001619.5

p.D10A

c.29A>C

1 paper

NM_001619.5

p.R27C

c.79C>T

1 paper

NM_001619.5

p.A9V

c.26C>T

2 papers

NM_001619.5

p.V7E

c.20T>A

4 papers

NM_001619.5

p.V7A

c.20T>C