Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001619.5

p.L34P

c.101T>C

Surrounding Variants

1 paper

NM_001619.5

p.I32I

c.96C>A

1 paper

NM_001619.5

p.E36Q

c.106G>C

1 paper

NM_001619.5

p.E36A

c.107A>C

1 paper

NM_001619.5

p.P37delFs

c.111delC

1 paper

NM_001619.5

p.P37L

c.110C>T

1 paper

NM_001619.5

p.S38fs

c.112_113fs

1 paper

NM_001619.5

p.S38Splc

c.113+1G>A

1 paper

NM_001619.5

p.R27C

c.79C>T

2 papers

NM_001619.5

p.A25T

c.73G>A

1 paper

NM_001619.5

p.E18E

c.54G>A

2 papers

NM_001619.5

p.E18A

c.53A>C

1 paper

NM_001619.5

p.E18V

c.53A>T