Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_001619.5

p.D110A

c.329A>C

Surrounding Variants

1 paper

NM_001619.5

p.Y112*

c.336C>A

1 paper

NM_001619.5

p.Y112*

c.336C>G

1 paper

NM_001619.5

p.I113F

c.337A>T

1 paper

NM_001619.5

p.R106L

c.317G>T

1 paper

NM_001619.5

p.E116A

c.347A>C

1 paper

NM_001619.5

p.R104H

c.311G>A

1 paper

NM_001619.5

p.R104C

c.310C>T

1 paper

NM_001619.5

p.C120*

c.360C>A

1 paper

NM_001619.5

p.C120W

c.360C>G

1 paper

NM_001619.5

p.T97T

c.291G>A

1 paper

NM_001619.5

p.E96A

c.287A>C

1 paper

NM_001619.5

p.L95P

c.284T>C