Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001619.5

p.R158Q

c.473G>A

Surrounding Variants

2 papers

NM_001619.5

p.R158*

c.472C>T

3 papers

NM_001619.5

p.L157F

c.469C>T

1 paper

NM_001619.5

p.D160Y

c.478G>T

1 paper

NM_001619.5

p.V161M

c.481G>A

1 paper

NM_001619.5

p.E151G

c.452A>G

2 papers

NM_001619.5

p.I166T

c.497T>C

1 paper

NM_001619.5

p.D144E

c.432T>A

1 paper

NM_001619.5

p.H131Q

c.393T>A

1 paper

NM_001619.5

p.E130A

c.389A>C

1 paper

NM_001619.5

p.F124L

c.372C>G

1 paper

NM_001619.5

p.C120*

c.360C>A

1 paper

NM_001619.5

p.C120W

c.360C>G