Varaico: Literature-Extracted Genetic Variants

GRK2

235 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates incl...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 2

HGNC Previous Symbol

ADRBK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001619.5

p.D481A

c.1442A>C

Surrounding Variants

2 papers

NM_001619.5

p.A480S

c.1438G>T

1 paper

NM_001619.5

p.A479V

c.1436C>T

2 papers

NM_001619.5

p.A479S

c.1435G>T

2 papers

NM_001619.5

p.D484A

c.1451A>C

2 papers

NM_001619.5

p.E476K

c.1426G>A

2 papers

NM_001619.5

p.R474*

c.1420C>T

2 papers

NM_001619.5

p.P473A

c.1417C>G

1 paper

NM_001619.5

p.P473S

c.1417C>T

2 papers

NM_001619.5

p.E490K

c.1468G>A

1 paper

NM_001619.5

p.P472A

c.1414C>G

1 paper

NM_001619.5

p.P469A

c.1405C>G

2 papers

NM_001619.5

p.G495A

c.1484G>C