Varaico: Literature-Extracted Genetic Variants

GRK3

94 papers

RefSeq Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 3

HGNC Previous Symbol

ADRBK2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 92 variants

4 papers

NM_005160.4

p.K644N

c.1932G>C

4 papers

NM_005160.4

p.K644N

c.1932G>T

2 papers

NM_005160.4

p.P148A

c.442C>G

2 papers

NM_005160.4

p.G442G

c.1326C>T

2 papers

NM_005160.4

p.R659H

c.1976G>A

1 paper

NM_005160.4

p.A2S

c.4G>T

1 paper

NM_005160.4

p.E18V

c.53A>T

1 paper

NM_005160.4

p.E18E

c.54G>A

1 paper

NM_005160.4

p.S38Splc

c.113+1G>A

1 paper

NM_005160.4

p.S41I

c.122G>T

1 paper

NM_005160.4

p.A48insFs

c.142_143ins4

1 paper

NM_005160.4

p.A48fs

c.142_143fs