Varaico: Literature-Extracted Genetic Variants

GRK3

94 papers

RefSeq Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 3

HGNC Previous Symbol

ADRBK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005160.4

p.E49insFs

c.146dupA

Surrounding Variants

1 paper

NM_005160.4

p.E49fs

c.145_146fs

1 paper

NM_005160.4

p.A48insFs

c.142_143ins4

1 paper

NM_005160.4

p.A48fs

c.142_143fs

1 paper

NM_005160.4

p.S41I

c.122G>T

1 paper

NM_005160.4

p.F59L

c.175T>C

1 paper

NM_005160.4

p.F59L

c.177C>A

1 paper

NM_005160.4

p.F59L

c.177C>G