Varaico: Literature-Extracted Genetic Variants

GRK3

94 papers

RefSeq Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 3

HGNC Previous Symbol

ADRBK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005160.4

p.K224_I227del4

c.670_680del12

Surrounding Variants

1 paper

NM_005160.4

p.K220R

c.659A>G

1 paper

NM_005160.4

p.K230R

c.689A>G

1 paper

NM_005160.4

p.E239Q

c.715G>C

1 paper

NM_005160.4

p.S247S

c.741C>T

1 paper

NM_005160.4

p.M216Splc

c.647+1G>A

1 paper

NM_005160.4

p.C208S

c.623G>C

1 paper

NM_005160.4

p.C208S

c.622T>A

1 paper

NM_005160.4

p.G201R

c.601G>A

1 paper

NM_005160.4

p.G201R

c.601G>C

1 paper

NM_005160.4

p.P252A

c.754C>G

1 paper

NM_005160.4

p.C256Y

c.767G>A

1 paper

NM_005160.4

p.T258A

c.772A>G