Varaico: Literature-Extracted Genetic Variants

GRK3

94 papers

RefSeq Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 3

HGNC Previous Symbol

ADRBK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005160.4

p.E360*

c.1078G>T

Surrounding Variants

1 paper

NM_005160.4

p.E360K

c.1078G>A

1 paper

NM_005160.4

p.S376P

c.1126T>C

1 paper

NM_005160.4

p.R386K

c.1157G>A

1 paper

NM_005160.4

p.A349V

c.1046C>T

1 paper

NM_005160.4

p.D341insFs

c.1022_1023insT

1 paper

NM_005160.4

p.D341N

c.1021G>A

1 paper

NM_005160.4

p.L338insFs

c.1012_1013insT

1 paper

NM_005160.4

p.A331T

c.991G>A

1 paper

NM_005160.4

p.D326insFs

c.977_978insC

1 paper

NM_005160.4

p.I323_L324insFs

c.969_970insG

1 paper

NM_005160.4

p.L318insFs

c.952_953insA

1 paper

NM_005160.4

p.Y315_R316insFs

c.945_946insC