Varaico: Literature-Extracted Genetic Variants

GRK3

94 papers

RefSeq Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 3

HGNC Previous Symbol

ADRBK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005160.4

p.G442G

c.1326C>T

Surrounding Variants

1 paper

NM_005160.4

p.G443C

c.1327G>T

1 paper

NM_005160.4

p.G441E

c.1322G>A

1 paper

NM_005160.4

p.C439Y

c.1316G>A

1 paper

NM_005160.4

p.H394H

c.1182T>C

1 paper

NM_005160.4

p.P473S

c.1417C>T

1 paper

NM_005160.4

p.D481A

c.1442A>C

1 paper

NM_005160.4

p.D492Y

c.1474G>T

1 paper

NM_005160.4

p.R386K

c.1157G>A

1 paper

NM_005160.4

p.S376P

c.1126T>C

1 paper

NM_005160.4

p.E360K

c.1078G>A

1 paper

NM_005160.4

p.E360*

c.1078G>T