Varaico: Literature-Extracted Genetic Variants

GRK3

94 papers

RefSeq Summary

The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2...

Pfam Domains

RGSaa 54–174UCSCRegulator of G protein signaling domain

Pkinaseaa 191–453UCSCProtein kinase domain

PHaa 559–652UCSCPH domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 3

HGNC Previous Symbol

ADRBK2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005160.4

p.N666S

c.1997A>G

Surrounding Variants

1 paper

NM_005160.4

p.K667E

c.1999A>G

1 paper

NM_005160.4

p.R669W

c.2005C>T

1 paper

NM_005160.4

p.R669P

c.2006G>C

1 paper

NM_005160.4

p.K663Q

c.1987A>C

1 paper

NM_005160.4

p.K663E

c.1987A>G

1 paper

NM_005160.4

p.R660H

c.1979G>A

2 papers

NM_005160.4

p.R659H

c.1976G>A

1 paper

NM_005160.4

p.K652T

c.1955A>C

1 paper

NM_005160.4

p.E646Q

c.1936G>C

1 paper

NM_005160.4

p.K645Q

c.1933A>C

4 papers

NM_005160.4

p.K644N

c.1932G>C

4 papers

NM_005160.4

p.K644N

c.1932G>T