G protein-coupled receptor kinase 4

GPRK2L

GPRK4

G protein-coupled receptor kinase 2-like (Drosophila)

G protein-coupled receptor kinase GRK4

ITI1

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013].

Varaico: Literature-Extracted Genetic Variants

GRK4

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol