Varaico: Literature-Extracted Genetic Variants

Gene:GRK4
Variant:p.V248A

GRK4

160 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms ...

Pfam Domains

RGSaa 52–171UCSCRegulator of G protein signaling domain
Pkinaseaa 187–449UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 4

HGNC Previous Symbol

GPRK2L

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_182982.3
p.V248A
c.743T>C
Surrounding Variants
3 papers
NM_182982.3
p.A253T
c.757G>A
1 paper
NM_182982.3
p.Y254H
c.760T>C
1 paper
NM_182982.3
p.H275H
c.825C>T
1 paper
NM_182982.3
p.G283S
c.847G>A
2 papers
NM_182982.3
p.G299S
c.895G>A
1 paper
NM_182982.3
p.E301K
c.901G>A
1 paper
NM_182982.3
p.N317K
c.951T>A
1 paper
NM_182982.3
p.N317K
c.951T>G
1 paper
NM_182982.3
p.L319L
c.957C>T
1 paper
NM_182982.3
p.V247_V248Splc
c.741+1G>A
5 papers
NM_182982.3
p.V247I
c.739G>A
1 paper
NM_182982.3
p.I223K
c.668T>A
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