Varaico: Literature-Extracted Genetic Variants

Gene:GRK4
Variant:p.G562D

GRK4

160 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms ...

Pfam Domains

RGSaa 52–171UCSCRegulator of G protein signaling domain
Pkinaseaa 187–449UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 4

HGNC Previous Symbol

GPRK2L

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_182982.3
p.G562D
c.1685G>A
Surrounding Variants
1 paper
NM_182982.3
p.C563S
c.1687T>A
1 paper
NM_182982.3
p.C563S
c.1688G>C
1 paper
NM_182982.3
p.C578S
c.1732T>A
1 paper
NM_182982.3
p.C578S
c.1733G>C
1 paper
NM_182982.3
p.A495insFs
c.1484_1485insG
1 paper
NM_182982.3
p.A495T
c.1483G>A
1 paper
NM_182982.3
p.I490T
c.1469T>C
12 papers
NM_182982.3
p.V486A
c.1457T>C
1 paper
NM_182982.3
p.D477A
c.1430A>C
1 paper
NM_182982.3
p.V473I
c.1417G>A
1 paper
NM_182982.3
p.H471Y
c.1411C>T
1 paper
NM_182982.3
p.P470L
c.1409C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."