Varaico: Literature-Extracted Genetic Variants

Gene:GRK5
Variant:p.T129M

GRK5

179 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms ...

Pfam Domains

RGSaa 52–170UCSCRegulator of G protein signaling domain
Pkinaseaa 186–448UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 5

HGNC Previous Symbol

GPRK5

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_005308.3
p.T129M
c.386C>T
Surrounding Variants
1 paper
NM_005308.3
p.S127F
c.380C>T
1 paper
NM_005308.3
p.G122S
c.364G>A
1 paper
NM_005308.3
p.C138S
c.412T>A
1 paper
NM_005308.3
p.C138S
c.413G>C
4 papers
NM_005308.3
p.A119V
c.356C>T
2 papers
NM_005308.3
p.L141I
c.421C>A
1 paper
NM_005308.3
p.L141R
c.422T>G
1 paper
NM_005308.3
p.F142Y
c.425T>A
1 paper
NM_005308.3
p.V116A
c.347T>C
1 paper
NM_005308.3
p.S143T
c.427T>A
1 paper
NM_005308.3
p.A144A
c.432C>T
1 paper
NM_005308.3
p.S114T
c.340T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."