Varaico: Literature-Extracted Genetic Variants

Gene:GRK6
Variant:p.E403D

GRK6

93 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms ...

Pfam Domains

RGSaa 52–170UCSCRegulator of G protein signaling domain
Pkinaseaa 186–448UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 6

HGNC Previous Symbol

GPRK6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001004106.3
p.E403D
c.1209G>C
Surrounding Variants
1 paper
NM_001004106.3
p.E403D
c.1209G>T
3 papers
NM_001004106.3
p.V404D
c.1211T>A
2 papers
NM_001004106.3
p.E406*
c.1216G>T
1 paper
NM_001004106.3
p.R399Q
c.1196G>A
1 paper
NM_001004106.3
p.R417C
c.1249C>T
1 paper
NM_001004106.3
p.K389T
c.1166A>C
2 papers
NM_001004106.3
p.P384S
c.1150C>T
1 paper
NM_001004106.3
p.I379I
c.1137C>T
1 paper
NM_001004106.3
p.Y376*
c.1128C>A
1 paper
NM_001004106.3
p.Y376*
c.1128C>G
1 paper
NM_001004106.3
p.S365T
c.1094G>C
1 paper
NM_001004106.3
p.V356A
c.1067T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."