Varaico: Literature-Extracted Genetic Variants

Gene:GRK6
Variant:p.L432L

GRK6

93 papers

RefSeq Summary

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms ...

Pfam Domains

RGSaa 52–170UCSCRegulator of G protein signaling domain
Pkinaseaa 186–448UCSCProtein kinase domain

Gene Aliases

HGNC Name

G protein-coupled receptor kinase 6

HGNC Previous Symbol

GPRK6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001004106.3
p.L432L
c.1296G>T
Surrounding Variants
1 paper
NM_001004106.3
p.G436E
c.1307G>A
2 papers
NM_001004106.3
p.E441K
c.1321G>A
1 paper
NM_001004106.3
p.P446R
c.1337C>G
1 paper
NM_001004106.3
p.F448L
c.1342T>C
1 paper
NM_001004106.3
p.F448L
c.1344T>A
1 paper
NM_001004106.3
p.F448L
c.1344T>G
2 papers
NM_001004106.3
p.P463A
c.1387C>G
1 paper
NM_001004106.3
p.R417C
c.1249C>T
2 papers
NM_001004106.3
p.E406*
c.1216G>T
3 papers
NM_001004106.3
p.V404D
c.1211T>A
1 paper
NM_001004106.3
p.E403D
c.1209G>C
1 paper
NM_001004106.3
p.E403D
c.1209G>T
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