Varaico: Literature-Extracted Genetic Variants

GRM2

124 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 60–460UCSCReceptor family ligand binding region

NCD3Gaa 495–546UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 561–813UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 2

HGNC Alias Symbols

GPRC1B; mGlu2; MGLUR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000839.5

p.M1K

c.2T>A

Surrounding Variants

1 paper

NM_000839.5

p.L5F

c.13C>T

1 paper

NM_000839.5

p.A6V

c.17C>T

1 paper

NM_000839.5

p.L11L

c.33G>A

1 paper

NM_000839.5

p.L12M

c.34C>A

2 papers

NM_000839.5

p.L12P

c.35T>C

1 paper

NM_000839.5

p.G20G

c.60C>G

1 paper

NM_000839.5

p.P39S

c.115C>T

6 papers

NM_000839.5

p.H41N

c.121C>A

1 paper

NM_000839.5

p.K43R

c.128A>G

1 paper

NM_000839.5

p.P46L

c.137C>T

1 paper

NM_000839.5

p.E55D

c.165G>C

1 paper

NM_000839.5

p.E55D

c.165G>T