Varaico: Literature-Extracted Genetic Variants

GRM2

124 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 60–460UCSCReceptor family ligand binding region

NCD3Gaa 495–546UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 561–813UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 2

HGNC Alias Symbols

GPRC1B; mGlu2; MGLUR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000839.5

p.E55D

c.165G>C

Surrounding Variants

1 paper

NM_000839.5

p.E55D

c.165G>T

1 paper

NM_000839.5

p.G58R

c.172G>C

1 paper

NM_000839.5

p.G58G

c.174C>T

1 paper

NM_000839.5

p.R61C

c.181C>T

1 paper

NM_000839.5

p.P46L

c.137C>T

1 paper

NM_000839.5

p.F67C

c.200T>G

1 paper

NM_000839.5

p.K43R

c.128A>G

1 paper

NM_000839.5

p.A68V

c.203C>T

6 papers

NM_000839.5

p.H41N

c.121C>A

1 paper

NM_000839.5

p.R71C

c.211C>T

1 paper

NM_000839.5

p.R71H

c.212G>A

1 paper

NM_000839.5

p.P39S

c.115C>T