Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.G24R

c.70G>C

Surrounding Variants

1 paper

NM_000840.3

p.G24R

c.70G>A

1 paper

NM_000840.3

p.G24E

c.71G>A

1 paper

NM_000840.3

p.S22Y

c.65C>A

1 paper

NM_000840.3

p.L21L

c.63C>G

8 papers

NM_000840.3

p.G18E

c.53G>A

2 papers

NM_000840.3

p.K17N

c.51G>C

2 papers

NM_000840.3

p.K17N

c.51G>T

1 paper

NM_000840.3

p.R30S

c.90G>C

1 paper

NM_000840.3

p.R30S

c.90G>T

1 paper

NM_000840.3

p.R31*

c.91A>T

1 paper

NM_000840.3

p.E32A

c.95A>C

1 paper

NM_000840.3

p.E32V

c.95A>T