Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_000840.3

p.R59Q

c.176G>A

Surrounding Variants

2 papers

NM_000840.3

p.R59*

c.175C>T

1 paper

NM_000840.3

p.G58R

c.172G>A

1 paper

NM_000840.3

p.G58R

c.172G>C

1 paper

NM_000840.3

p.G58W

c.172G>T

1 paper

NM_000840.3

p.E55K

c.163G>A

1 paper

NM_000840.3

p.R64Q

c.191G>A

1 paper

NM_000840.3

p.G53E

c.158G>A

1 paper

NM_000840.3

p.G53R

c.157G>A

1 paper

NM_000840.3

p.G53R

c.157G>C

2 papers

NM_000840.3

p.G51fs

c.151_152fs

1 paper

NM_000840.3

p.L69L

c.205C>T

3 papers

NM_000840.3

p.E49K

c.145G>A