Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.Y184F

c.551A>T

Surrounding Variants

3 papers

NM_000840.3

p.D185N

c.553G>A

3 papers

NM_000840.3

p.R183C

c.547C>T

3 papers

NM_000840.3

p.S182L

c.545C>T

1 paper

NM_000840.3

p.K181T

c.542A>C

1 paper

NM_000840.3

p.K181E

c.541A>G

1 paper

NM_000840.3

p.R189S

c.567G>C

1 paper

NM_000840.3

p.R189S

c.567G>T

1 paper

NM_000840.3

p.P193insFs

c.579dupC

1 paper

NM_000840.3

p.P193insFs

c.578_579dupCC

1 paper

NM_000840.3

p.P193delFs

c.579delC

1 paper

NM_000840.3

p.P192T

c.574C>A

1 paper

NM_000840.3

p.A176A

c.528C>G