Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.E203K

c.607G>A

Surrounding Variants

1 paper

NM_000840.3

p.A202A

c.606T>G

1 paper

NM_000840.3

p.M201I

c.603G>A

1 paper

NM_000840.3

p.M201I

c.603G>C

1 paper

NM_000840.3

p.M201I

c.603G>T

3 papers

NM_000840.3

p.R206C

c.616C>T

1 paper

NM_000840.3

p.F207Y

c.620T>A

1 paper

NM_000840.3

p.D194A

c.581A>C

1 paper

NM_000840.3

p.D194fs

c.580_581fs

1 paper

NM_000840.3

p.P193S

c.577C>T

2 papers

NM_000840.3

p.V213M

c.637G>A

1 paper

NM_000840.3

p.P192L

c.575C>T

1 paper

NM_000840.3

p.P192T

c.574C>A