Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.T225S

c.673A>T

Surrounding Variants

1 paper

NM_000840.3

p.G226E

c.677G>A

1 paper

NM_000840.3

p.I227I

c.681C>T

2 papers

NM_000840.3

p.E228K

c.682G>A

1 paper

NM_000840.3

p.E228Q

c.682G>C

1 paper

NM_000840.3

p.G220C

c.658G>T

1 paper

NM_000840.3

p.E219K

c.655G>A

2 papers

NM_000840.3

p.E231G

c.692A>G

1 paper

NM_000840.3

p.E233G

c.698A>G

1 paper

NM_000840.3

p.E233D

c.699A>C

1 paper

NM_000840.3

p.S214F

c.641C>T

3 papers

NM_000840.3

p.R237C

c.709C>T

2 papers

NM_000840.3

p.V213M

c.637G>A