Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.R237_N238delins

c.711_712delinsAT

Surrounding Variants

1 paper

NM_000840.3

p.N238Y

c.712A>T

2 papers

NM_000840.3

p.R237H

c.710G>A

3 papers

NM_000840.3

p.R237C

c.709C>T

1 paper

NM_000840.3

p.C240*

c.720C>A

1 paper

NM_000840.3

p.E233D

c.699A>C

1 paper

NM_000840.3

p.E233G

c.698A>G

2 papers

NM_000840.3

p.E231G

c.692A>G

2 papers

NM_000840.3

p.A244S

c.730G>T

1 paper

NM_000840.3

p.A244V

c.731C>T

1 paper

NM_000840.3

p.V247L

c.739G>C

1 paper

NM_000840.3

p.V247L

c.739G>T

2 papers

NM_000840.3

p.E228K

c.682G>A