Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.Q265fs

c.793_794fs

Surrounding Variants

1 paper

NM_000840.3

p.Q265_R270delFs

c.794_810del17

1 paper

NM_000840.3

p.P267L

c.800C>T

1 paper

NM_000840.3

p.E262K

c.784G>A

1 paper

NM_000840.3

p.A269P

c.805G>C

1 paper

NM_000840.3

p.A269E

c.806C>A

1 paper

NM_000840.3

p.I260M

c.780C>G

1 paper

NM_000840.3

p.A269G

c.806C>G

1 paper

NM_000840.3

p.R270C

c.808C>T

2 papers

NM_000840.3

p.V271I

c.811G>A

1 paper

NM_000840.3

p.V272L

c.814G>C

1 paper

NM_000840.3

p.V272L

c.814G>T

3 papers

NM_000840.3

p.D257N

c.769G>A