Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.R277C

c.829C>T

Surrounding Variants

1 paper

NM_000840.3

p.R277S

c.829C>A

1 paper

NM_000840.3

p.R277H

c.830G>A

1 paper

NM_000840.3

p.F275F

c.825C>T

1 paper

NM_000840.3

p.F275V

c.823T>G

1 paper

NM_000840.3

p.D279E

c.837C>A

1 paper

NM_000840.3

p.D279E

c.837C>G

2 papers

NM_000840.3

p.D280N

c.838G>A

1 paper

NM_000840.3

p.S281L

c.842C>T

1 paper

NM_000840.3

p.R282W

c.844C>T

1 paper

NM_000840.3

p.V272L

c.814G>C

1 paper

NM_000840.3

p.V272L

c.814G>T

2 papers

NM_000840.3

p.V271I

c.811G>A