Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000840.3

p.D301A

c.902A>C

Surrounding Variants

1 paper

NM_000840.3

p.A299A

c.897C>A

1 paper

NM_000840.3

p.A299V

c.896C>T

1 paper

NM_000840.3

p.A299T

c.895G>A

1 paper

NM_000840.3

p.G304G

c.912C>A

1 paper

NM_000840.3

p.G304G

c.912C>T

1 paper

NM_000840.3

p.V298M

c.892G>A

1 paper

NM_000840.3

p.A305T

c.913G>A

1 paper

NM_000840.3

p.A305V

c.914C>T

1 paper

NM_000840.3

p.F295F

c.885C>T

1 paper

NM_000840.3

p.S308T

c.923G>C

2 papers

NM_000840.3

p.A293A

c.879C>T

1 paper

NM_000840.3

p.A293V

c.878C>T