Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.A320T

c.958G>A

Surrounding Variants

1 paper

NM_000840.3

p.A320D

c.959C>A

1 paper

NM_000840.3

p.A320V

c.959C>T

1 paper

NM_000840.3

p.G319S

c.955G>A

1 paper

NM_000840.3

p.E324Q

c.970G>C

1 paper

NM_000840.3

p.E314D

c.942G>C

1 paper

NM_000840.3

p.E314D

c.942G>T

1 paper

NM_000840.3

p.E314K

c.940G>A

1 paper

NM_000840.3

p.Q328insFs

c.982dupC

1 paper

NM_000840.3

p.S327F

c.980C>T

1 paper

NM_000840.3

p.Q328fs

c.982_983fs

1 paper

NM_000840.3

p.Q328H

c.984G>C

1 paper

NM_000840.3

p.Q328H

c.984G>T