Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.N341S

c.1022A>G

Surrounding Variants

1 paper

NM_000840.3

p.L340H

c.1019T>A

1 paper

NM_000840.3

p.Y343C

c.1028A>G

1 paper

NM_000840.3

p.Y343*

c.1029C>A

1 paper

NM_000840.3

p.Y343*

c.1029C>G

1 paper

NM_000840.3

p.F337_Q338ins1

c.1011_1012insAGT

1 paper

NM_000840.3

p.F337_Q338ins2

c.1011_1012ins6

1 paper

NM_000840.3

p.H346L

c.1037A>T

1 paper

NM_000840.3

p.R347C

c.1039C>T

3 papers

NM_000840.3

p.R335H

c.1004G>A

1 paper

NM_000840.3

p.P349delFs

c.1047delC

1 paper

NM_000840.3

p.P349L

c.1046C>T

2 papers

NM_000840.3

p.R331H

c.992G>A