Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.G464V

c.1391G>T

Surrounding Variants

1 paper

NM_000840.3

p.G464R

c.1390G>A

1 paper

NM_000840.3

p.G464R

c.1390G>C

4 papers

NM_000840.3

p.R465*

c.1393C>T

1 paper

NM_000840.3

p.G462V

c.1385G>T

1 paper

NM_000840.3

p.G462R

c.1384G>A

1 paper

NM_000840.3

p.G462R

c.1384G>C

1 paper

NM_000840.3

p.G460R

c.1378G>A

1 paper

NM_000840.3

p.G460R

c.1378G>C

1 paper

NM_000840.3

p.T458A

c.1372A>G

1 paper

NM_000840.3

p.D457H

c.1369G>C

7 papers

NM_000840.3

p.G475D

c.1424G>A

1 paper

NM_000840.3

p.D451delFs

c.1353delT