Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.L490*

c.1469T>G

Surrounding Variants

1 paper

NM_000840.3

p.L490*

c.1469T>A

1 paper

NM_000840.3

p.S496T

c.1486T>A

1 paper

NM_000840.3

p.G484D

c.1451G>A

1 paper

NM_000840.3

p.R501W

c.1501C>T

1 paper

NM_000840.3

p.S479A

c.1435T>G

1 paper

NM_000840.3

p.P505S

c.1513C>T

1 paper

NM_000840.3

p.P505H

c.1514C>A

7 papers

NM_000840.3

p.G475D

c.1424G>A

1 paper

NM_000840.3

p.S510S

c.1530C>T

1 paper

NM_000840.3

p.D511N

c.1531G>A

1 paper

NM_000840.3

p.C513S

c.1537T>A

1 paper

NM_000840.3

p.C513S

c.1538G>C