Varaico: Literature-Extracted Genetic Variants

GRM3

337 papers

RefSeq Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in mo...

Pfam Domains

ANF_receptoraa 67–474UCSCReceptor family ligand binding region

NCD3Gaa 504–555UCSCNine Cysteines Domain of family 3 GPCR

7tm_3aa 570–822UCSC7 transmembrane sweet-taste receptor of 3 GCPR

Gene Aliases

HGNC Name

glutamate metabotropic receptor 3

HGNC Alias Symbols

GPRC1C; mGlu3; MGLUR3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000840.3

p.V526F

c.1576G>T

Surrounding Variants

1 paper

NM_000840.3

p.D525N

c.1573G>A

1 paper

NM_000840.3

p.C528S

c.1582T>A

1 paper

NM_000840.3

p.C528G

c.1582T>G

1 paper

NM_000840.3

p.C528S

c.1583G>C

1 paper

NM_000840.3

p.P523fs

c.1567_1568fs

1 paper

NM_000840.3

p.P523delFs

c.1568delC

1 paper

NM_000840.3

p.M521I

c.1563G>A

1 paper

NM_000840.3

p.M521I

c.1563G>C

1 paper

NM_000840.3

p.M521I

c.1563G>T

1 paper

NM_000840.3

p.K519R

c.1556A>G

5 papers

NM_000840.3

p.M518I

c.1554G>A

5 papers

NM_000840.3

p.M518I

c.1554G>C